Journal of International Medical Research (Aug 2023)

Evaluation of splenic infarction ratio and platelet increase ratio after partial splenic artery embolization

  • Junji Ueda,
  • Yasuhiro Mamada,
  • Nobuhiko Taniai,
  • Masato Yoshioka,
  • Akira Matsushita,
  • Satoshi Mizutani,
  • Youichi Kawano,
  • Tetsuya Shimizu,
  • Tomohiro Kanda,
  • Hideyuki Takata,
  • Hiroyasu Furuki,
  • Yuto Aoki,
  • Manpei Kawashima,
  • Toshiyuki Irie,
  • Takashi Ohno,
  • Takahiro Haruna,
  • Hiroshi Yoshida

DOI
https://doi.org/10.1177/03000605231190967
Journal volume & issue
Vol. 51

Abstract

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Objective The spleen is part of the lymphatic system and is one of the least understood organs of the human body. It is involved in the production of blood cells and helps filter the blood, remove old blood cells, and fight infection. Partial splenic artery embolization (PSE) is widely used to treat pancytopenia and portal hypertension. The efficacy of PSE for improving thrombocytopenia has been well demonstrated. In this study, we evaluated the splenic infarction ratio and platelet increase ratio after PSE. Methods Forty-five consecutive patients underwent PSE from January 2014 to August 2022. We retrospectively evaluated the splenic infarction volume and ratio after PSE and analyzed the relationship between the splenic infarction ratio and platelet increase ratio after PSE. Results The platelet increase ratio was correlated with the splenic infarction ratio after PSE. The cutoff value for the splenic infarction ratio with a two-fold platelet increase was 63.0%. Conclusion We suggest performance of PSE in patients with a splenic infarction ratio of 63% to double the expected platelet count.