Nature Communications (Sep 2022)

Wireless multi-lateral optofluidic microsystems for real-time programmable optogenetics and photopharmacology

  • Yixin Wu,
  • Mingzheng Wu,
  • Abraham Vázquez-Guardado,
  • Joohee Kim,
  • Xin Zhang,
  • Raudel Avila,
  • Jin-Tae Kim,
  • Yujun Deng,
  • Yongjoon Yu,
  • Sarah Melzer,
  • Yun Bai,
  • Hyoseo Yoon,
  • Lingzi Meng,
  • Yi Zhang,
  • Hexia Guo,
  • Liu Hong,
  • Evangelos E. Kanatzidis,
  • Chad R. Haney,
  • Emily A. Waters,
  • Anthony R. Banks,
  • Ziying Hu,
  • Ferrona Lie,
  • Leonardo P. Chamorro,
  • Bernardo L. Sabatini,
  • Yonggang Huang,
  • Yevgenia Kozorovitskiy,
  • John A. Rogers

DOI
https://doi.org/10.1038/s41467-022-32947-0
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 15

Abstract

Read online

Wireless delivery of both light and pharmacological agents is important for optogenetic and other mechanistic experiments in the brain. Here the authors present a wireless real-time programmable optofluidic platform that enables optogenetics and photopharmacology experiments that require real-time precise control of light and drug delivery.