Nature Communications (Sep 2022)
Wireless multi-lateral optofluidic microsystems for real-time programmable optogenetics and photopharmacology
- Yixin Wu,
- Mingzheng Wu,
- Abraham Vázquez-Guardado,
- Joohee Kim,
- Xin Zhang,
- Raudel Avila,
- Jin-Tae Kim,
- Yujun Deng,
- Yongjoon Yu,
- Sarah Melzer,
- Yun Bai,
- Hyoseo Yoon,
- Lingzi Meng,
- Yi Zhang,
- Hexia Guo,
- Liu Hong,
- Evangelos E. Kanatzidis,
- Chad R. Haney,
- Emily A. Waters,
- Anthony R. Banks,
- Ziying Hu,
- Ferrona Lie,
- Leonardo P. Chamorro,
- Bernardo L. Sabatini,
- Yonggang Huang,
- Yevgenia Kozorovitskiy,
- John A. Rogers
Affiliations
- Yixin Wu
- Department of Materials Science and Engineering, Northwestern University
- Mingzheng Wu
- Department of Neurobiology, Northwestern University
- Abraham Vázquez-Guardado
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Joohee Kim
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Xin Zhang
- Department of Neurobiology, Northwestern University
- Raudel Avila
- Department of Mechanical Engineering, Northwestern University
- Jin-Tae Kim
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Yujun Deng
- Department of Mechanical Engineering, Northwestern University
- Yongjoon Yu
- Neurolux Inc
- Sarah Melzer
- Department of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School
- Yun Bai
- Department of Materials Science and Engineering, Northwestern University
- Hyoseo Yoon
- Department of Neurobiology, Northwestern University
- Lingzi Meng
- Department of Materials Science and Engineering, Northwestern University
- Yi Zhang
- Polymer Program, Institute of Materials Science, University of Connecticut
- Hexia Guo
- Department of Materials Science and Engineering, Northwestern University
- Liu Hong
- Mechanical Science and Engineering Department, University of Illinois
- Evangelos E. Kanatzidis
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Chad R. Haney
- Center for Advanced Molecular Imaging, Radiology, and Biomedical Engineering, Northwestern University
- Emily A. Waters
- Center for Advanced Molecular Imaging, Radiology, and Biomedical Engineering, Northwestern University
- Anthony R. Banks
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Ziying Hu
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Ferrona Lie
- Neurolux Inc
- Leonardo P. Chamorro
- Mechanical Science and Engineering Department, University of Illinois
- Bernardo L. Sabatini
- Department of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School
- Yonggang Huang
- Department of Materials Science and Engineering, Northwestern University
- Yevgenia Kozorovitskiy
- Department of Neurobiology, Northwestern University
- John A. Rogers
- Department of Materials Science and Engineering, Northwestern University
- DOI
- https://doi.org/10.1038/s41467-022-32947-0
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 15
Abstract
Wireless delivery of both light and pharmacological agents is important for optogenetic and other mechanistic experiments in the brain. Here the authors present a wireless real-time programmable optofluidic platform that enables optogenetics and photopharmacology experiments that require real-time precise control of light and drug delivery.