A high level of fatigue among long-term survivors of non-Hodgkin’s lymphoma: results from the longitudinal population-based PROFILES registry in the south of the Netherlands
Simone Oerlemans,
Floortje Mols,
Djamila E. Issa,
J. H. F. M. Pruijt,
Wim G. Peters,
Marnix Lybeert,
Wobbe Zijlstra,
Jan Willem W. Coebergh,
Lonneke V. van de Poll-Franse
Affiliations
Simone Oerlemans
Comprehensive Cancer Centre South, Eindhoven;Center of Research on Psychology in Somatic Diseases (CoRPS), Tilburg University, Tilburg
Floortje Mols
Comprehensive Cancer Centre South, Eindhoven;Center of Research on Psychology in Somatic Diseases (CoRPS), Tilburg University, Tilburg
Djamila E. Issa
Dept. of Hematology, VU University Medical Center, Amsterdam
J. H. F. M. Pruijt
Dept. of Oncology and Hematology, Jeroen Bosch Hospital, ‘s-Hertogenbosch
Wim G. Peters
Dept. of Oncology and Hematology, Catharina-Hospital, Eindhoven
Marnix Lybeert
Dept. of Radiation Oncology, Catharina-Hospital, Eindhoven
Wobbe Zijlstra
Center of Research on Psychology in Somatic Diseases (CoRPS), Tilburg University, Tilburg;Dept. of Methodology and Statistics, Tilburg University, Tilburg
Jan Willem W. Coebergh
Comprehensive Cancer Centre South, Eindhoven;Dept. of Public Health, Erasmus University Medical Centre, Rotterdam, the Netherlands
Lonneke V. van de Poll-Franse
Comprehensive Cancer Centre South, Eindhoven;Center of Research on Psychology in Somatic Diseases (CoRPS), Tilburg University, Tilburg
The course of fatigue and quality of life in survivors of non-Hodgkin’s lymphoma is unknown. The aims of this study were, therefore, to assess fatigue and quality of life in patients with non-Hodgkin’s lymphoma following primary treatment, compare fatigue and quality of life in these patients with those of an age- and sex matched normative population to assess the severity of concerns and identify associations with fatigue of survivors who remained fatigued. The population-based Eindhoven Cancer Registry was used to select all patients diagnosed with non-Hodgkin’s lymphoma from 1999–2009. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire and the Fatigue Assessment Scale were completed once by 824 survivors of non-Hodgkin’s lymphoma (80% response rate); 434 survivors completed these questionnaires again 1 year later. Survivors of non-Hodgkin’s lymphoma reported more clinically relevant fatigue up till 10 years post-diagnosis compared to a normative population (P
