A retrospective study of 3D deep learning approach incorporating coordinate information to improve the segmentation of pre- and post-operative abdominal aortic aneurysm

Abstract

Abdominal aortic aneurysm (AAA) is one of the most common diseases worldwide. 3D segmentation of AAA provides useful information for surgical decisions and follow-up treatment. However, existing segmentation methods are time consuming and not practical in routine use. In this article, the segmentation task will be addressed automatically using a deep learning based approach which has been proved to successfully solve several medical imaging problems with excellent performances. This article therefore proposes a new solution of AAA segmentation using deep learning in a type of 3D convolutional neural network (CNN) architecture that also incorporates coordinate information. The tested CNNs are UNet, AG-DSV-UNet, VNet, ResNetMed and DenseVoxNet. The 3D-CNNs are trained with a dataset of high resolution (256 × 256) non-contrast and post-contrast CT images containing 64 slices from each of 200 patients. The dataset consists of contiguous CT slices without augmentation and no post-processing step. The experiments show that incorporation of coordinate information improves the segmentation results. The best accuracies on non-contrast and contrast-enhanced images have average dice scores of 97.13% and 96.74%, respectively. Transfer learning from a pre-trained network of a pre-operative dataset to post-operative endovascular aneurysm repair (EVAR) was also performed. The segmentation accuracy of post-operative EVAR using transfer learning on non-contrast and contrast-enhanced CT datasets achieved the best dice scores of 94.90% and 95.66%, respectively.

Keywords

• Abdominal aortic aneurysm
• Computed tomography
• 3D segmentation
• Deep learning
• Coordinate information
• Transfer learning