Severe hypoxemia after Stanford A aortic dissection surgery: a clinical analysis of 162 cases

Abstract

Objective To investigate the risk factors for post-operative severe hypoxemia in patients with Stanford A aortic dissection. Methods Clinical data of 162 patients with Stanford A aortic dissection undergoing surgical treatment in our hospital from January 2016 to March 2019 were collected and retrospectively analyzed in this study. According to their oxygenation index(PaO2/FiO2) within 72 h after operation, they were divided into severe hypoxia group (≤100 mmHg) and non-severe hypoxemia group(>100 mmHg). The perioperative clinical indexes were compared between the 2 groups, and the risk factors of severe hypoxemia were analyzed. Results The incidence of severe hypoxemia was 50.6%(82/162) in the cohort. The severe hypoxia group had significantly longer time of mechanical ventilation, postoperative length of ICU stay and hospital stay when compared with the non-severe hypoxia group(all P 24 kg/m2(OR=2.604, 95%CI: 1.055~6.427, P=0.038), preoperative PaO2/FiO2≤300 mmHg(OR=2.963, 95%CI: 1.283~6.841, P=0.011) and cardiopulmonary bypass(CPB) time >195 min(OR=1.007, 95%CI: 1.000~1.014, P 24 kg/m2, preoperative PaO2/FiO2≤300 mmHg and CPB time>195 min are independent risk factors for post-operative severe hypoxemia after surgery of Stanford type A aortic dissection.

Keywords

• hypoxemia
• aortic dissection
• risk factors