Nature Communications (Sep 2020)

Relative configuration of micrograms of natural compounds using proton residual chemical shift anisotropy

  • Nilamoni Nath,
  • Juan Carlos Fuentes-Monteverde,
  • Dawrin Pech-Puch,
  • Jaime Rodríguez,
  • Carlos Jiménez,
  • Markus Noll,
  • Alexander Kreiter,
  • Michael Reggelin,
  • Armando Navarro-Vázquez,
  • Christian Griesinger

DOI
https://doi.org/10.1038/s41467-020-18093-5
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 9

Abstract

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Determination of 3D molecular structures remains challenging for natural products or organic compounds available in minute amounts. Here, the authors determine the structure of complex molecules, including few micrograms of briarane B-3 isolated from Briareum asbestinums, through measurement of 1H residual chemical shift anisotropy.