Nature Communications (Jun 2021)

Crystal structure of an archaeal CorB magnesium transporter

  • Yu Seby Chen,
  • Guennadi Kozlov,
  • Brandon E. Moeller,
  • Ahmed Rohaim,
  • Rayan Fakih,
  • Benoît Roux,
  • John E. Burke,
  • Kalle Gehring

DOI
https://doi.org/10.1038/s41467-021-24282-7
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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CNNM/CorB proteins are a conserved family of membrane proteins associated with Mg2+ transport. Here, structures of an archaeal CorB protein in apo state and with Mg2+-ATP bound and accompanying biophysical experiments suggest direct Mg2+ transport by CorB proteins.