T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development

• Charles E. de Bock,
• Michelle Down,
• Kinsha Baidya,
• Bram Sweron,
• Andrew W. Boyd,
• Mark Fiers,
• Gordon F. Burns,
• Timothy J. Molloy,
• Richard B. Lock,
• Jean Soulier,
• Tom Taghon,
• Pieter Van Vlierberghe,
• Jan Cools,
• Jeff Holst,
• Rick F. Thorne

Affiliations

Charles E. de Bock

KU Leuven, Center for Human Genetics, Belgium;VIB, Center for Cancer Biology, Leuven, Belgium

Michelle Down

Leukaemia Foundation Laboratory, QIMR-Berghofer Medical Research Institute, Brisbane, Australia

Kinsha Baidya

School of Medical Sciences and Prince of Wales Clinical School, University of New South Wales, Sydney, Australia

Bram Sweron

KU Leuven, Center for Human Genetics, Belgium;VIB, Center for Cancer Biology, Leuven, Belgium

Andrew W. Boyd

Leukaemia Foundation Laboratory, QIMR-Berghofer Medical Research Institute, Brisbane, Australia

Mark Fiers

VIB-KU Leuven Center for Brain & Disease Research, Belgium

Gordon F. Burns

Cancer Research Unit, The University of Newcastle, Callaghan, NSW, Australia

Timothy J. Molloy

St Vincent’s Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia

Richard B. Lock

Children’s Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, Australia

Jean Soulier

U944 INSERM and Hematology laboratory, St-Louis Hospital, APHP, Hematology University Institute, University Paris-Diderot, France

Tom Taghon

Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Belgium

Pieter Van Vlierberghe

Center for Medical Genetics, Ghent University Hospital, Belgium Cancer Research Institute Ghent (CRIG), Belgium

Jan Cools

KU Leuven, Center for Human Genetics, Belgium;VIB, Center for Cancer Biology, Leuven, Belgium

Jeff Holst

Translational Cancer Metabolism Laboratory, Lowy Cancer Research Centre, University of New South Wales, Sydney, Australia

Rick F. Thorne

Translational Research Institute, Henan Provincial People’s Hospital, School of Medicine, Henan University, Zhengzhou, China;School of Environmental and Life Sciences, University of Newcastle, NSW, Australia