Frontiers in Bioinformatics (May 2025)

pubCounteR: an R package for interrogating published literature for experimentally-derived gene lists within a user-defined biological context

  • Marina Leer,
  • Marina Leer,
  • George A. Soultoukis,
  • George A. Soultoukis,
  • Markus Jähnert,
  • Markus Jähnert,
  • Masoome Oveisi,
  • Masoome Oveisi,
  • Dirk Walther,
  • Tim J. Schulz,
  • Tim J. Schulz,
  • Tim J. Schulz

DOI
https://doi.org/10.3389/fbinf.2025.1523184
Journal volume & issue
Vol. 5

Abstract

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Basic and clinical biomedical research relies heavily on modern large-scale datasets that include genomics, transcriptomics, epigenomics, metabolomics, and proteomics, among other “Omics”. These research tools very often generate lists of candidate genes that are hypothesized or shown to be responsible for the biological effect in question. To aid the biological interpretation of experimentally-obtained gene lists, we developed pubCounteR, an R-package and web-based interface that screens publications by a user-defined set of keywords representing a specific biological context for experimentally-derived gene lists.

Keywords