Antibacterial Potential of Cascabela Thevatica Leaf Extract Against Escherichia Coli- A Study In Vitro

Abstract

Cascabela thevatica leaf part was tested for antibacterial efficacy against Escherichia coli organism using the disc diffusion method. The crude alcoholic extract was found effective against Escherichia coli organism. The antibacterial activity is attributed to the presence of alkaloids, which was confirmed by gas chromatography end positive alkaloid test. The minimum inhibitory concentration (MIC) was determined for the crude extract by paper disc diffusion method. The result were compared with reference antibiotic tetracycline (one unit strength).

Keywords

• Cascabela thevatica
• Escherichia coli
• Apocynaceae
• Leaf extract
• Antibacterial
• Antimicrobial activity.