Nature Communications (Oct 2022)
Effectiveness of an inactivated Covid-19 vaccine with homologous and heterologous boosters against Omicron in Brazil
- Otavio T. Ranzani,
- Matt D. T. Hitchings,
- Rosana Leite de Melo,
- Giovanny V. A. de França,
- Cássia de Fátima R. Fernandes,
- Margaret L. Lind,
- Mario Sergio Scaramuzzini Torres,
- Daniel Henrique Tsuha,
- Leticia C. S. David,
- Rodrigo F. C. Said,
- Maria Almiron,
- Roberto D. de Oliveira,
- Derek A. T. Cummings,
- Natalie E. Dean,
- Jason R. Andrews,
- Albert I. Ko,
- Julio Croda
Affiliations
- Otavio T. Ranzani
- Barcelona Institute for Global Health, ISGlobal, Universitat Pompeu Fabra (UPF)
- Matt D. T. Hitchings
- Department of Biostatistics, College of Public Health & Health Professions, University of Florida
- Rosana Leite de Melo
- Secretaria Extraordinária de Enfrentamento à Covid-19, Ministério da Saúde
- Giovanny V. A. de França
- Secretaria de Vigilância em Saúde, Ministério da Saúde
- Cássia de Fátima R. Fernandes
- Secretaria de Vigilância em Saúde, Ministério da Saúde
- Margaret L. Lind
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Mario Sergio Scaramuzzini Torres
- Municipal Health Secretary of Manaus
- Daniel Henrique Tsuha
- Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz
- Leticia C. S. David
- Pan American Health Organization
- Rodrigo F. C. Said
- Pan American Health Organization
- Maria Almiron
- Pan American Health Organization
- Roberto D. de Oliveira
- State University of Mato Grosso do Sul
- Derek A. T. Cummings
- Department of Biology, University of Florida
- Natalie E. Dean
- Department of Biostatistics & Bioinformatics, Rollins School of Public Health, Emory University
- Jason R. Andrews
- Division of Infectious Diseases and Geographic Medicine, Stanford University
- Albert I. Ko
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Julio Croda
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- DOI
- https://doi.org/10.1038/s41467-022-33169-0
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 10
Abstract
This study investigates the effectiveness of COVID-19 vaccine boosters following a primary series of CoronaVac vaccination. Using data from Brazil during the Omicron wave, the authors show that boosters provided protection against severe disease, with higher effectiveness from a BNT162b2 than CoronaVac booster.
