Nature Communications (Jul 2018)

Single olfactory receptors set odor detection thresholds

  • Adam Dewan,
  • Annika Cichy,
  • Jingji Zhang,
  • Kayla Miguel,
  • Paul Feinstein,
  • Dmitry Rinberg,
  • Thomas Bozza

DOI
https://doi.org/10.1038/s41467-018-05129-0
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 12

Abstract

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Odorous chemicals broadly activate subsets of olfactory receptors in the nose, but how individual receptors contribute to behavioral sensitivity is not clear. Here, the authors demonstrate that detection thresholds in mice are set solely by the highest affinity receptor for a given odorant.