Escherichia coli ST1193 O75 H5: A rare cause of native valve endocarditis with multifocal emboli to brain and spleen
Diana M. Villanueva,
John R. Lonks,
Sara Geffert,
Sophia Panaccione,
Jerome Larkin,
Swapna Charla,
Jennifer Li,
Tao Hong
Affiliations
Diana M. Villanueva
Division of Infectious Diseases, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA
John R. Lonks
Division of Infectious Diseases, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA
Sara Geffert
Division of Infectious Diseases, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA; Microbiology Laboratory, Department of Pathology and Laboratory Medicine, Rhode Island Hospital, Providence, RI 02903, USA; Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA
Sophia Panaccione
Division of Infectious Diseases, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA
Jerome Larkin
Division of Infectious Diseases, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA
Swapna Charla
Microbiology Laboratory, Department of Pathology and Laboratory Medicine, Rhode Island Hospital, Providence, RI 02903, USA
Jennifer Li
Microbiology Laboratory, Department of Pathology and Laboratory Medicine, Rhode Island Hospital, Providence, RI 02903, USA
Tao Hong
Microbiology Laboratory, Department of Pathology and Laboratory Medicine, Rhode Island Hospital, Providence, RI 02903, USA; Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA; Correspondence to: 593 Eddy Street, Providence, RI 02903, USA.
Escherichia coli (E. coli) is a facultative anaerobic gram-negative rod bacterium, which can acquire pathogenicity through the acquisition of additional genetic material. We present a case of E. coli ST1193, an emerging global multidrug-resistant (MDR) high-risk clone, causing native valve endocarditis and septic brain and splenic emboli in a 67-year-old woman.