ACS Omega
(Aug 2018)
Altering Nitrogen Heterocycles of AZD2461 Affords High Affinity Poly(ADP-ribose) Polymerase‑1 Inhibitors with Decreased P‑Glycoprotein Interactions
- Sean W. Reilly,
- Laura N. Puentes,
- Chia-Ju Hsieh,
- Mehran Makvandi,
- Robert H. Mach
Affiliations
- Sean W. Reilly
- Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States
- Laura N. Puentes
- Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, United States
- Chia-Ju Hsieh
- Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States
- Mehran Makvandi
- Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States
- Robert H. Mach
- Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States
- DOI
-
https://doi.org/10.1021/acsomega.8b00896
- Journal volume & issue
-
Vol. 3,
no. 8
pp.
9997
– 10001
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