Changes in bacterial profiles after periodontal treatment associated with respiratory quality of asthmatic children

Abstract

Background Despite the reduction phenomenon of asthma exacerbation after dental plaque control, no scientific report has been found to describe the link between bacterial profiles and respiratory quality in children with asthma. Objective To investigate association between bacterial profiles changes and improvement in respiratory quality after periodontal treatment. Methods Asthmatic children with FEV1 reversibility ~ 12% and dental plaque index ~ 2 who qualified for inclusion criteria were randomized into two groups. The treatment group was referred for dental plaque removal by oral biology dentist and guided to perform an individual oral health care for seven days. The control group was observed without intervention. Each subject was assessed for respiratory quality and bacterial profiles taken from plaque culture before and after one week run-in period. Paired t-test and correlation were used for statistical anayses. The study protocol was approved by the Medical Research Ethics Committee of Dr. Soetomo Hospital. Results Dental plaque control was performed in 18 of 36 children with mild asthma. At follow-up, plaque analysis among the subjects receiving dental treatment showed a significant reduction (P0.4; P<0.05) with bacterial profiles changes after periodontal treatment. Conclusions A reduced rate of gram negative bacilli colonization in dental plaque after periodontal treatment is related to improvement of respiratory quality of asthmatic children.

Keywords

• asthma
• dental plaque
• FEY1 reversibility
• bacteria