1,4-Diurea- and 1,4-Dithiourea-Substituted Aromatic Derivatives Selectively Inhibit α‑Synuclein Oligomer Formation In Vitro
Susantha K. Ganegamage,
Eduardo Ramirez,
Heba Alnakhala,
Arati Tripathi,
Cuong Calvin Duc Nguyen,
Ashique Zami,
Raluca Ostafe,
Shiliang Tian,
Ulf Dettmer,
Jessica S. Fortin
Affiliations
Susantha K. Ganegamage
Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana, United States
Eduardo Ramirez
Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana, United States
Heba Alnakhala
Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States
Arati Tripathi
Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States
Cuong Calvin Duc Nguyen
Department of Chemistry, College of Sciences, Purdue University, West Lafayette, Indiana, United States
Ashique Zami
Purdue Institute for Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, Indiana, United States
Raluca Ostafe
Purdue Institute for Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, Indiana, United States
Shiliang Tian
Department of Chemistry, College of Sciences, Purdue University, West Lafayette, Indiana, United States
Ulf Dettmer
Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States
Jessica S. Fortin
Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana, United States