Hyperuricemia is Related to the Risk of Cardiovascular Diseases in Ethnic Chinese Elderly Women
Leilei Liu,
Xiao Zhang,
Lian Peng,
Nana Ma,
Tingting Yang,
Chan Nie,
Linyuan Zhang,
Zixuan Xu,
Jun Yang,
Xuejie Tang,
Liubo Zheng,
Tao Zhang,
Feng Hong
Affiliations
Leilei Liu
School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 550025
Xiao Zhang
School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 550025; Center for Diseases Control and Prevention of Yunyan District, Guiyang 550004
Lian Peng
School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 550025
Nana Ma
School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 550025
Tingting Yang
School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 550025
Chan Nie
School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 550025
Linyuan Zhang
School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 550025
Zixuan Xu
School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 550025
Jun Yang
Guiyang Center for Diseases Control and Prevention, Guiyang 550003
Xuejie Tang
The Higher Education Mega Center Hospital, Guizhou Medical University, Guiyang 550025
Guiyang Public Health Clinical Center, Guiyang 550004
Feng Hong
School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 550025
Background: The association between hyperuricemia (HUA) and cardiovascular diseases (CVDs) is not fully elucidated. Objective: To assess the relationship according to factors of sex and age in the Chinese ethnic groups. Methods: We performed a population–based cross-sectional study in a multi-ethnic population from southwestern China. HUA patients were identified by serum uric acid ≥7 mg/dL in men and 6 mg/dL in women. The outcome was composite prevalent CVDs, including coronary heart disease (CHD), stroke, and arrhythmia. Multivariate logistic regression analysis, estimating odds ratio (ORs) and 95% confidence intervals (CIs), were applied to evaluate the HUA–CVDs relationship. Results: We included 16,618 people (37.48% Dong, 30.00% Miao, and 32.52% Bouyei) aged 30–79 years without a reduced estimated glomerular filtration rate 50 years, a 55% (1.55, 1.00–2.39) and 65% (1.65, 1.02–2.66) increased risk for CVDs was observed in Dong and Bouyei ethnicities. Conclusions: HUA may be related to an increased risk of CVDs among women in the Dong and Bouyei ethnic groups in China, especially women aged > 50 years.
