Hyperuricemia is Related to the Risk of Cardiovascular Diseases in Ethnic Chinese Elderly Women

Abstract

Background: The association between hyperuricemia (HUA) and cardiovascular diseases (CVDs) is not fully elucidated. Objective: To assess the relationship according to factors of sex and age in the Chinese ethnic groups. Methods: We performed a population–based cross-sectional study in a multi-ethnic population from southwestern China. HUA patients were identified by serum uric acid ≥7 mg/dL in men and 6 mg/dL in women. The outcome was composite prevalent CVDs, including coronary heart disease (CHD), stroke, and arrhythmia. Multivariate logistic regression analysis, estimating odds ratio (ORs) and 95% confidence intervals (CIs), were applied to evaluate the HUA–CVDs relationship. Results: We included 16,618 people (37.48% Dong, 30.00% Miao, and 32.52% Bouyei) aged 30–79 years without a reduced estimated glomerular filtration rate 50 years, a 55% (1.55, 1.00–2.39) and 65% (1.65, 1.02–2.66) increased risk for CVDs was observed in Dong and Bouyei ethnicities. Conclusions: HUA may be related to an increased risk of CVDs among women in the Dong and Bouyei ethnic groups in China, especially women aged > 50 years.

Keywords

• hyperuricemia
• cardiovascular diseases
• ethnic difference
• women
• elderly