Scientific Reports (Oct 2022)

Cold intolerance and associated factors: a population study

  • Alireza Khabbazi,
  • Rojin Farzaneh,
  • Maryam Mahmoudi,
  • Mohammad Shahi,
  • Amirreza Jabbaripour Sarmadian,
  • Elaheh Babapour,
  • Leila Alizadeh,
  • Raha Khabbazi,
  • Masoud Nouri-Vaskeh

DOI
https://doi.org/10.1038/s41598-022-21842-9
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 6

Abstract

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Abstract Cold intolerance has been defined as a set of symptoms including pain, tingling, numbness, chills, stiffness, weakness, swelling or skin color changes on exposure to cold. Cold intolerance may have a profound effect on health-related quality of life. In this cross-sectional study, we investigated primarily the prevalence of cold intolerance and secondly associated factors in the general population of Tabriz. Simple random sampling of individuals aged ≥ 18 was performed from the population covered by Emamieh health center under the supervision of Tabriz University of Medical Sciences. A telephone interview was conducted with the participants by the general physician of that center. In participants with a positive response to each of two questions “I am oversensitive to cold” and “I experience pain or discomfort when exposed to cold” a Cold Intolerance Symptom Severity (CISS) questionnaire was filled. We used a cut off value 50 for defining cold intolerance. Of the 353 person who received telephone calls, 322 answered questions. Cold related symptoms and cold intolerance were reported in 144 (44.7%) and 38 (11.1%) persons, respectively. Cold intolerance was significantly more common in females and people with comorbidities. Cold intolerance led to a decrease in quality of job in 27 (8.4%) and a change in job in 6 (1.9%) persons. In conclusion, cold intolerance is a common problem in the general population of Tabriz.