Nature Communications (Apr 2017)

Refined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales

  • Claude Bhérer,
  • Christopher L. Campbell,
  • Adam Auton

DOI
https://doi.org/10.1038/ncomms14994
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 9

Abstract

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It is known that males have lower recombination rates than females over much of the genome but little is known about differences at a fine scale. Here the authors combine data from over 100,000 meioses and show that the majority of differences can be explained by variation in hotspot magnitude.