Nature Communications (May 2018)

The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation

  • Fabien Soulavie,
  • David H. Hall,
  • Meera V. Sundaram

DOI
https://doi.org/10.1038/s41467-018-04091-1
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 11

Abstract

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Membrane fusion and fission events at exoplasmic membrane surfaces are not well understood. Here the authors show that the C. elegans cell–cell fusogen AFF-1 is required for endocytic scission and apically-directed membrane trafficking during the development of a unicellular tube.