The role of neoadjuvant chemotherapy in patients with advanced (stage IIIC) epithelial ovarian cancer

Abstract

Primary treatment of patients with advanced epithelial ovarian cancer consists of chemotherapy either before (neoadjuvant chemotherapy, NACT) or after primary surgery (adjuvant chemotherapy). The goal of primary treatment is no residual disease after surgery (R0 resection) what is associated with an improvement in survival of patients. There is, however, no evidence of survival benefits in patients with R0 resections after prior NACT.

Keywords

• advanced ovarian cancer
• neoadjuvant chemotherapy
• primary surgery