Nature Communications (Apr 2021)

Automatic synchronisation of the cell cycle in budding yeast through closed-loop feedback control

  • Giansimone Perrino,
  • Sara Napolitano,
  • Francesca Galdi,
  • Antonella La Regina,
  • Davide Fiore,
  • Teresa Giuliano,
  • Mario di Bernardo,
  • Diego di Bernardo

DOI
https://doi.org/10.1038/s41467-021-22689-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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It is difficult to synchronize the cell cycle in a population of yeast cells for extended periods of time. Here the authors use a cybergenetic system with inbuilt feedback to synchronize a population of modified yeast.