GAIMS Journal of Medical Sciences (Jun 2023)
Orofacial histoplasmosis in a patient with AIDS: a case report
Abstract
Histoplasmosis, also known as Darling's disease, is a fungal infection caused by Histoplasma capsulatum and is common among patients with AIDS and is mainly found in North, Central and South America and sub-Saharan Africa. It manifests as pulmonary, progressive disseminated histoplasmosis involving reticuloendothelial system, liver, spleen, lymph node, bone marrow, adrenal glands and primary cutaneous histoplasmosis. In HIV infection, 10% cases of histoplasmosis have cutaneous manifestations. Only 12 reports of AIDS associated histoplasmosis are described in the Indian literature. In this report, we describe an additional case of histoplasmosis in 19-year-old male in Kutch district of Gujarat state.
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