Factors associated with 10-m walking speed in outpatients undergoing hemodialysis: a multicenter cross-sectional study

Abstract

Abstract Introduction Walking ability is an important prognostic factor for patients undergoing maintenance hemodialysis (HD). Since complications such as poor nutrition, anemia, malnutrition, and inflammation in patients undergoing HD may affect walking ability, the factors affected by 10-m walking speed must be investigated. This cross-sectional study enrolled 1205 outpatients undergoing HD and measured their 10-m walking speed. Methods Lower extremity muscle strength (LES), grip strength, one-leg standing time (OLST), and short physical performance battery (SPPB) score were measured as physical functions. Age, sex, body mass index, dialysis history, comorbidities, and hematological data were collected. Results A multiple regression analysis revealed that the 10-m walking speed was significantly associated with LES, grip strength, OLST, SPPB, and % creatinine production rate, even after adjusting for corresponding variables (R 2 = 0.69, p < 0.05). Conclusion Muscle strength and muscle mass may be essential factors for the 10-m walking speed in patients undergoing HD.

Keywords

• 10-m walking speed
• Hemodialysis
• Muscle strength
• Muscle mass