Acta Cirúrgica Brasileira (Jun 2020)

Hepathic, biochemical, hematological, and histological effects of the ultracavitation in rabbits livers

  • Patrícia Froes Meyer,
  • Janiele Ferreira da Silva Sousa,
  • Rejane Vilar da Rocha,
  • José Queiroz Filho,
  • Oscar Ariel Ronzio,
  • Rodrigo Marcel Valentim da Silva,
  • Ana Camila de Medeiros Manso,
  • Afra Rafaelli Magalhães de Almeida,
  • Camila Procopio Andrada

DOI
https://doi.org/10.1590/s0102-865020200040000003
Journal volume & issue
Vol. 35, no. 4

Abstract

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Abstract Purpose To collect data capable of pointing out the effects of the ultracavitation treatment on the liver of rabbits after adipose tissue application, by means of histological analyses of the liver and hematological and biochemical exams. Methods This is an experimental study with 12 albino rabbits as sample, which were divided into 3 groups and submitted to a hypercaloric diet for one month. Subsequently, subjects underwent UCV treatment: 3 minutes, 30 W, continuous mode at 100%, every 2 ERAS = 441.02 J/cm2, intensity of 10w/cm2. They were then euthanized and underwent biopsy after 24 hours. Results After 48 hours from the ultracavitation treatment, the animals’ livers presented greater amount of fat infiltration if compared to the amount presented 96 hours after the treatment. However, laboratory tests showed no alterations. Values were maintained within normal parameters of cholesterol, triglycerides, liver enzymes, hemoglobin and hematocrit levels. Conclusions This study has identified that infiltrates may appear on livers after the treatment, despite high hematological and biochemical tests results. The fat infiltrates reduction 96 h after treatment suggests lower risks to animal health, if the period between applications is respected.

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