EFFECTIVE MANAGEMENT OF PULMONARY TUBERCULOSIS COMPLICATED WITH MYCOBACTERIAL DRUG RESISTANCE IN THE REPUBLIC OF BURYATIA

Abstract

We present the results of treatment of patients with primary multidrug resistant pulmonary tuberculosis (MDR PT) (main group) and with acquiring MDR PT (comparison group) in Republic of Buryatia. We used the indexes for estimation of the treatment results according to the international standard. Index of sputum clean negativations is higher in main group - 77,8 %, in comparison, group - 44,4 %. The rate of negative sputum, in main group was 78 %, in comparison group - 41,9 % (р < 0,01). Increasing of drug resistance to reserved, medication up to MDR were often in the 2nd group (21/10,3 %). Tolerability to reserved, medication, in the 1st group was better than in the 2nd group (28 % and. 43,4 % correspondingly, р < 0,05). In 24 months there were 26 % recovered patients in the 1st group and. 10,8 % in the 2nd group (р

Keywords

• mycobacterium tuberculosis
• treatment
• multidrug resistance