Limited Nosocomial Transmission of Drug-Resistant Tuberculosis, Moldova

Abstract

Applying whole-genome-sequencing, we aimed to detect transmission events of multidrug-resistant/rifampin-resistant strains of Mycobacterium tuberculosis complex at a tuberculosis hospital in Chisinau, Moldova. We recorded ward, room, and bed information for each patient and monitored in-hospital transfers over 1 year. Detailed molecular and patient surveillance revealed only 2 nosocomial transmission events.

Keywords

• tuberculosis and other mycobacteria
• multidrug-resistant tuberculosis
• rifampin-resistant tuberculosis
• TB
• Moldova
• WGS