Nonsyndromic solitary neurofibromas in the oral cavity: Case series and literature review

Abstract

Neurogenic tumors are rare in the oral cavity. Solitary neurofibroma is a rare benign nonodontogenic tumor which may present either as a solitary lesion or as part of the generalized syndrome of neurofibromatosis or von Recklinghausen's disease of the skin. Clinically, oral neurofibromas present as pedunculated or sessile nodules, with slow growth, mostly without pain or paresthesia unless a neural compression occurs. The diagnosis can be confirmed by histological examination. Immunopositivity for the S-100 protein indicates its neural origin. Surgical excision is the treatment of choice and the prognosis is excellent.

Keywords

• Neurofibroma
• nonodontogenic tumor
• von Recklinghausen's disease