Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia

Abstract

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Central pontine myelinolysis (CPM) is a heterogeneous nervous system disease of pontine demyelination, usually caused by rapid correction of hyponatremia. In the present study, we report a unique case of a 46-year-old man with a hyperglycemic state complicated with CPM. MRI demonstrated a high signal on T2 and symmetric restricted diffusion in the pontine. In conclusion, the clinical case described confirmed that the hyperosmolar state inherent in hyperglycemia was a likely cause of CPM.

Keywords

• central pontine myelinolysis
• hyponatremia
• hyperosmolar
• osmotic demyelination syndrome
• blood glucose