Current Medicine Research and Practice (Jan 2013)
Extra-osseous osteogenic sarcoma arising from the retroperitoneum: A dangerous and rare entity
Abstract
A 34-year-old shopkeeper with a mass in the right lower abdomen was admitted to our hospital. He had minimal symptoms despite the large size of the tumour. Contrast CT scan with angiography revealed a soft tissue tumour arising from the right psoas muscle with dense sunray spiculated ossification which was suggestive of soft tissue osteosarcoma arising from the right psoas muscle. Excision of the mass along with the involved portion of the psoas muscle was performed and the patient was sent for chemotherapy. Histopathology revealed proliferation of malignant cells and malignant osteoid. He came back 3 months later with a complete block in the right external iliac artery. Involvement of the retroperitoneum is rare among the extra-osseous osteogenic sarcoma arising from the somatic soft tissue. Only 12 cases have been reported in the literature as being of retroperitoneal origin, and no patient has survived for 5 years, indicating its dismal prognosis.
