PLoS ONE (Jan 2019)

Association between serum 25-hydroxyvitamin D and diabetic kidney disease in Chinese patients with type 2 diabetes.

  • Shaofeng Xie,
  • Liji Huang,
  • Wen Cao,
  • Yongxin Hu,
  • Hongping Sun,
  • Lin Cao,
  • Kemian Liu,
  • Chao Liu

DOI
https://doi.org/10.1371/journal.pone.0214728
Journal volume & issue
Vol. 14, no. 4
p. e0214728

Abstract

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ObjectiveThe objective was to assess the association between 25-hydroxyvitamin D (25OHD) level and diabetic kidney disease (DKD) in Chinese patients with type 2 diabetes.MethodsData pertaining to 351 in-patients with type 2 diabetes were collected. Subjects were classified into three groups based on the level of urinary albumin-to-creatinine ratio (UACR). UACR ResultsThe prevalence of 25OHD insufficiency in the microalbuminuria group was significantly higher than that in the normoalbuminuria group (25.1% vs. 19.6%; P ConclusionsThe prevalence of vitamin D insufficiency/deficiency in patients with albuminuria was overtly higher than that in patients without albuminuria among Chinese adults with type 2 diabetes. Vitamin D insufficiency/deficiency was independently associated with DKD in type 2 diabetes.