The role of oxidative stress in the formation of postmenopausal osteoporosis

Abstract

In the present review discusses the impact of oxidative stress on bone metabolism. Shows the importance of pro-oxidants in the physiology and pathology of bone remodelling. Key role oxidative stress begins to play in post-menopausal. This is due to a decrease in estrogen levels and the formation of involutional changes in the body, including bone metabolism. Furthermore, the article addresses the issues of antioxidant protection involved in maintaining bone homeostasis.

Keywords

• reactive oxygen species
• pro-oxidants
• lipid peroxidation
• oxidative stress
• antioxidants
• osteoporosis