Проблемы особо опасных инфекций (Jun 2008)
F(ab’)<sub>2</sub>-Fragments of Antirabic Immunoglobulin Production Using Immobilized Pepsin
Abstract
Biotechnological scheme for F(ab')2-fragments of anti-rabies immunoglobulin production using immobilized pepsin was developed. Optimal ways for immobilized pepsin production were determined, conditions for fermentative hydrolysis of anti-rabies immunoglobulin were sorted out. Protective properties of F(ab')2-fragments of anti-rabies immunoglobulin produced by means of this method were assessed.
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