BMJ Open (Feb 2025)
Impact of insurance coverage for non-vitamin K antagonist oral anticoagulants on quality of care and care disparities in patients hospitalised with atrial fibrillation in tertiary hospitals in China: interrupted time series analysis
- ,
- Jing Liu,
- Hong Liu,
- Shaoping Nie,
- Huifang Zhang,
- Jian Yang,
- Ling Li,
- Bin Li,
- Wei Liu,
- Tao Zhang,
- Yan Wang,
- Bin Liu,
- Hui Liu,
- Na Yang,
- Wei Wang,
- Zuyi Yuan,
- Xiaoli Yang,
- Yang Yu,
- Bing Han,
- Weiting Xu,
- Hong Jiang,
- Yong Li,
- Hong Zhang,
- Hua Jiang,
- Jun Liu,
- Lin Wang,
- Bo Yu,
- Jie Yang,
- Tao Liu,
- Man Zhang,
- Yue Li,
- Ping Zhang,
- Weihong Jiang,
- Jie Chen,
- Yingxian Sun,
- Xi Su,
- Yaling Han,
- Zheng Zhang,
- Xianghua Fu,
- Chuanyu Gao,
- Bao Li,
- Jiyan Chen,
- Yitong Ma,
- Xingsheng Zhao,
- Junbo Ge,
- Junmin Liu,
- Zhaoqing Sun,
- Xiaojun Wang,
- Jing Xu,
- Xue Li,
- Jie Jiang,
- Bin Wang,
- Lan Huang,
- Ruiping Zhao,
- Qiang Wu,
- Xia Chen,
- Jianfeng Ye,
- Xiaofei Sun,
- Yi Huang,
- Ping Hou,
- Tianlun Yang,
- Ping Chen,
- Zhirong Wang,
- Di Wu,
- Pengfei Zhang,
- Peng Qu,
- Yanli Wang,
- Jianhao Li,
- Kaihong Chen,
- Hui Dong,
- Xiaochun Ma,
- Guo Li,
- Jun Guan,
- Zhenyu Yang,
- Yingzhong Lin,
- Xiaoping Chen,
- Dong Zhao,
- Rong Lin,
- Daoquan Peng,
- Xuebo Liu,
- Hongwei Li,
- Jingfeng Wang,
- Yang Zheng,
- Ying Guo,
- Weijun Wang,
- Xiaoshu Cheng,
- Ping Xie,
- Ling Tao,
- Lang Hong,
- Tianchang Li,
- Yongchen Hao,
- Yin Liu,
- Lirong Wu,
- Fanju Meng,
- Xiaowen Ma,
- Pingshuan Dong,
- Zhaofa He,
- Yuemin Sun,
- Junping Fang,
- Fang Zhao,
- Guoqing Li,
- Yuhua Zhu,
- Biao Xu,
- Weijian Huang,
- Xianxian Zhao,
- Changqian Wang,
- Guosheng Fu,
- Fengwei Li,
- Nan Jia,
- Lin Wei,
- Wenhua Lin,
- Yulan Zhao,
- Xiaohui Liu,
- Juexin Fan,
- Lv Qiang,
- Jinchuan Yan,
- Lilong Tang,
- Genshan Ma,
- Zhiyuan Song,
- Jiayi Tong,
- Jiawang Ding,
- Xiangjun Yang,
- Aiping Li,
- Dongyan Li,
- Yong Guo,
- Xin Tang,
- Zhijian Yang,
- Jianwen Liu,
- Xiaoqin Zhang,
- Yuehua Huang,
- Guizhou Tao,
- Shenghu He,
- Moshui Chen,
- Zhiming Yang,
- Haiping Guo,
- Xuming Yang,
- Chuntong Wang,
- Xiaoyong Qi,
- Hong Luan,
- Qiang Xie,
- Dongmei Zhu,
- Yuanzhe Jin,
- Likun Ma,
- Xiaoling Su,
- Yongle Li,
- Deyong Long,
- Baisong Yang,
- Gengsheng Sang,
- Bing Fu,
- Buqiang Zhang,
- Caidong Luo,
- Changrong Liu,
- Chuanliang Liang,
- Chuanyan Zhang,
- Chuanyang Wu,
- Chunlin Lai,
- Congliang Zhang,
- Cui Bin,
- Dawen Xu,
- Fangfang Huang,
- Fudong Gan,
- Gengxin Li,
- Guixia Zhang,
- Guoqin Xin,
- Guotuo Chen,
- Guoxiong Chen,
- Hailong Lin,
- Haiyun Lin,
- Honghua Deng,
- Hongju Wang,
- Hualing Liu,
- Huifeng Wang,
- Huimin Chu,
- Jianghong Tao,
- Jiaomei Yang,
- Jifu Li,
- Jinglan Diao,
- Jingshan Zhao,
- Jinru Wei,
- Jinxing Yi,
- Jinzi Su,
- Jiong Tang,
- Dangqing Yu,
- Jiyan Yin,
- Junping Deng,
- Kalan Luo,
- Lang Li,
- Li Wei Li Jiang,
- Lijun Meng,
- Junqiang Cao,
- Meisheng Lai,
- Miao Tian,
- Mingcheng Bo,
- Minghua Han,
- Naiyi Liang,
- Qiaoqing Zhong,
- Dajun Hu,
- Qicun Wang,
- Qinfeng Su,
- Qing Hu,
- Rong Chang,
- Shaowu Ye,
- Zhaohua Lu,
- Shengxing Tang,
- Shengyong Chen,
- Shixin Ma,
- Shuangbin Li,
- Shuanli Xin,
- Shudong Xia,
- Shuhua Zhang,
- Shuqiu Qu,
- Shuren Ma,
- Siding Wang,
- Songbai Li,
- Suxin Luo,
- Suyan Zhou,
- Tian Tuo,
- Tianmin Du,
- Wei Tuo,
- Weiqing Fan,
- Wenjun Yuan,
- Xian’an Zhang,
- Xiaolan Li,
- Xiaolei Li,
- Xiaoping Xu,
- Xiaowei Peng,
- Xiaoyun Feng,
- Ximing Chen,
- Xiufeng Chen,
- Xudong Li,
- Xuemei Peng,
- Yanbo Niu,
- Yanlie Zheng,
- Yanzong Yang,
- Liangqing Ge,
- Jianqiang Peng,
- Yingbi Su,
- Yingchao Luo,
- Yinglu Hao,
- Yonglin Zhang,
- Yuhuan Shi,
- Yuqing Hou,
- Zeqi Zheng,
- Zesheng Xu,
- Zewei Ouyang,
- Zeyuan He,
- Zhan Lv,
- Zhanquang Li,
- Zheng Ji,
- Zhenguo Ji,
- Zhihong Ou,
- Zhongshan Wang
Affiliations
- Jing Liu
- 6 Department of Nursing, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China
- Hong Liu
- Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan Province, China
- Shaoping Nie
- Center for Coronary Artery Disease, Division of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China
- Huifang Zhang
- 1 Department of Acupuncture and Moxibustion, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China
- Jian Yang
- Department of Cardiovascular Surgery, Xijing Hospital, Air Force Medical University, Xi`an, Shaanxi, China
- Ling Li
- 1 Department of Endocrinology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
- Bin Li
- Biliary Tract Surgery Department I, Eastern Hepatobiliary Surgery Hospital, Secondary Military Medicine University, Shanghai, China
- Wei Liu
- 2 Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore
- Tao Zhang
- 3 Beijing Genomics Institute (BGI)-Shenzhen, Shenzhen, China
- Yan Wang
- Value & Implementation, Global Medical & Scientific Affairs, Merck Sharp & Dohme (MSD) China, Shanghai, China
- Bin Liu
- 1David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
- Hui Liu
- Department of Respiratory and Critical Care Medicine, The Eighth Affiliated Hospital of Sun Yat-Sen University, Shenzhen, China
- Na Yang
- Department of Epidemiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China
- Wei Wang
- Department of Neurology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, People`s Republic of China
- Zuyi Yuan
- 2 Department of Cardiovascular Medicine, First Affiliated Hospital of Medical School, Xi’an Jiaotong University, Xi’an, China
- Xiaoli Yang
- Department of Clinical Laboratory, The Third Medical Center of Chinese PLA General Hospital, Beijing, Beijing, China
- Yang Yu
- The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China
- Bing Han
- 1Shanghai Cell Therapy Group Co. Ltd, Shanghai, China
- Weiting Xu
- Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China
- Hong Jiang
- Department of Structural Heart Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People`s Republic of China
- Yong Li
- Department of Oncology, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, China
- Hong Zhang
- 3 Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA
- Hua Jiang
- 1 Institute for Emergency and Disaster Medicine, Sichuan Academy of Medical Science, Sichuan Provincial People`s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China
- Jun Liu
- Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, Guangdong, China
- Lin Wang
- Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China
- Bo Yu
- Department of ENT and Head & Neck Surgery, Children`s Hospital,Zhejiang University School of Medicine, Hangzhou, China
- Jie Yang
- Department of Neurology, Xinqiao Hospital and the Second Affiliated Hospital of Army Medical University, Chongqing, China
- Tao Liu
- 1Shanghai Jiliang Biotechnology Inc, Shanghai, China
- Man Zhang
- Department of Hematology, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, Heilongjiang, China
- Yue Li
- Key Laboratory of Human Microbiome and Chronic Diseases, Ministry of Education, Sun Yat-Sen University, Guangzhou, Guangdong, China
- Ping Zhang
- Department of Nephrology, Sichuan Provincial People’s Hospital, Chengdu, China
- Weihong Jiang
- Department of Otolaryngology Head and Neck Surgery, Central South University, Changsha, Hunan, China
- Jie Chen
- professor
- Yingxian Sun
- Department of Cardiovascular Medicine, The First Hospital of China Medical University, Shenyang, China
- Xi Su
- Wuhan Asian Heart Hospital, Wuhan, China
- Yaling Han
- Department of Cardiology, General Hospital of Shenyang Military Region, Shenyang, Liaoning, China
- Zheng Zhang
- Department of Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, People`s Republic of China
- Xianghua Fu
- 9 Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, China
- Chuanyu Gao
- Department of Cardiology, Fuwai Central China Cardiovascular Hospital, Zhengzhou, Henan, China
- Bao Li
- 11 Department of Cardiology, Shanxi Cardiovascular Hospital, Taiyuan, China
- Jiyan Chen
- Cardiology, Guangdong General Hospital, Guangzhou, Guangdong, China
- Yitong Ma
- 14 Department of Cardiology, The First Affiliated Hospital of Xinjiang Medical University, Urumchi, China
- Xingsheng Zhao
- 15 Department of Cardiology, Inner Mongolia People’s Hospital, Hohhot, China
- Junbo Ge
- 2 Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases; National Clinical Research Center for Interventional Medicine, Shanghai, China
- Junmin Liu
- 2 Imaging Research Laboratories, Robarts Research Institute, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada
- Zhaoqing Sun
- Department of Cardiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China
- Xiaojun Wang
- 1 Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
- Jing Xu
- 7 School of Journalism and Communications, Peking University, Beijing, China
- Xue Li
- 1 Department of Head and Neck Surgery, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Jie Jiang
- Public Research Center, Hainan Medical University, Haikou, Hainan, China
- Bin Wang
- 7 Department of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
- Lan Huang
- Department of Palliative Medicine, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China
- Ruiping Zhao
- Qiang Wu
- Department of Cardiology, Xuzhou Central Hospital, Xuzhou, Jiangsu, China
- Xia Chen
- 13 Central Laboratory of the Medical Research Center, The First Affiliated Hospital of Ningbo University, Ningbo, People`s Republic of China
- Jianfeng Ye
- Department of Cardiology, Dongguan TCM Hospital, Dongguan, China
- Xiaofei Sun
- 4 Mental Health Education and Counseling Center, Hangzhou Normal University, Hangzhou, China
- Yi Huang
- Wuhu Hospital of Traditional Chinese Medicine, Wuhu, Anhui, China
- Ping Hou
- 1 School of Biomedical Engineering, School of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China
- Tianlun Yang
- Department of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, China
- Ping Chen
- 1 Department of Oncology, Chengdu Seventh People`s Hospital (Affiliated Cancer Hospital of Chengdu Medical College), Chengdu, Sichuan, China
- Zhirong Wang
- Ophthalmic Center State Key Laboratory of Ophthalmology, Sun Yat-Sen University Zhongshan, Guangzhou, Guangdong, China
- Di Wu
- 2 Xinjiang Medical University, Urumqi, Xinjiang, China
- Pengfei Zhang
- 1 State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China
- Peng Qu
- Yanli Wang
- Department of Nutrition and Food Hygiene, School of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China
- Jianhao Li
- Department of Cardiology, Central Hospital of Panyu District, Guangzhou, China
- Kaihong Chen
- Department of Cardiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China
- Hui Dong
- Department of Pathology, Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai, People`s Republic of China
- Xiaochun Ma
- Department of Critical Care Medicine, The First Hospital of China Medical University, Shenyang, China
- Guo Li
- Department of Psychocardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China
- Jun Guan
- 1Incyte Research Institute, Wilmington, DE, USA
- Zhenyu Yang
- 1 National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China
- Yingzhong Lin
- Department of Cardiology, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China
- Xiaoping Chen
- Department of Cardiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
- Dong Zhao
- Department of Epidemiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China
- Rong Lin
- Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Daoquan Peng
- Department of Cardiovascular Medicine, Second Xiangya Hospital of Central South University, Changsha, Hunan, China
- Xuebo Liu
- Department of Cardiology, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, China
- Hongwei Li
- Department of Cardiology, Sun Yat-Sen University Sun Yat-Sen Memorial Hospital, Guangzhou, Guangdong, China
- Jingfeng Wang
- Department of Cardiology, Sun Yat-Sen University Sun Yat-Sen Memorial Hospital, Guangzhou, Guangdong, China
- Yang Zheng
- Cardiovascular Disease Center, the First Hospital of Jilin University, Jilin, China
- Ying Guo
- Shanghai Baoshan District Wusong Central Hospital (Zhongshan Hospital Wusong Branch, Fudan University), Shanghai, China
- Weijun Wang
- Department of Ophthalmology, Shanghai General Hospital, Shanghai, China
- Xiaoshu Cheng
- Cardiovascular Department, The Second Affiliated Hospital of Nanchang University, Nanchang, China
- Ping Xie
- 1 Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
- Ling Tao
- 4 Xinxiang Medical University, Xinxiang, Henan, China
- Lang Hong
- 22 Department of Cardiology, Jiangxi Provincial People’s Hospital, Nanchang, Jiangxi, China
- Tianchang Li
- 3Tongren Hospital, Capital Medical University
- Yongchen Hao
- Department of Epidemiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China
- Yin Liu
- technician
- Lirong Wu
- Fanju Meng
- Xiaowen Ma
- 1 Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas, USA
- Pingshuan Dong
- Zhaofa He
- Yuemin Sun
- Junping Fang
- Fang Zhao
- Cambridge Institute for Medical Research, Addenbrooke`s Hospital, Cambridge, CB2 0XY, UK
- Guoqing Li
- Obstetrics and Gynecology Hospital, NHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), State Key Laboratory of Genetic Engineering at School of Life Sciences, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai, China
- Yuhua Zhu
- Department of Gastroenterology, Provincial Hospital Affiliated to Shandong University, Jinan, China
- Biao Xu
- Department of Epidemiology, School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai, China
- Weijian Huang
- 3 Department of Cardiology, The First Hospital affiliated to Wenzhou Medical College, Wenzhou, China
- Xianxian Zhao
- 4 Department of Cardiology, Changhai Hospital affiliated to Second Military Medical University, Shanghai, China
- Changqian Wang
- 6 Department of Cardiology, Shanghai Ninth People’s Hospital affiliated to Shanghai Jiao Tong University, Shanghai, China
- Guosheng Fu
- Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
- Fengwei Li
- 3 Department of Thoracic Surgery, Beijing Aerospace General Hospital, Beijing, China
- Nan Jia
- Department of Nephrology, Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, China
- Lin Wei
- 2 Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, Guangdong, China
- Wenhua Lin
- First Department of Cardiology, TEDA International Cardiovascular Hospital, Tianjin, China
- Yulan Zhao
- Departments of Pathology
- Xiaohui Liu
- Department of Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China
- Juexin Fan
- Department of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China
- Lv Qiang
- 2Capital Medical University, Affiliated Beijing Anzhen Hospital
- Jinchuan Yan
- The Affiliated Hospital of Jiangsu University
- Lilong Tang
- Division of Cardiology, The Fifth Affiliated Hospital to Sun Yat-Sen University, Zhuhai, Guangdong, China
- Genshan Ma
- 2Institute of Cardiology of Zhongda Hospital
- Zhiyuan Song
- 1Southwest Hospital
- Jiayi Tong
- 2Institute of Cardiology of Zhongda Hospital
- Jiawang Ding
- 2Department of Cardiology, The First College of Clinical Medical Sciences, China Three Gorges University
- Xiangjun Yang
- Aiping Li
- Department of Molecular Cell Biology and Toxicology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Cancer Centre, School of Public Health, Nanjing Medical University, Nanjing, People`s Republic of China
- Dongyan Li
- Department of Respiration, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
- Yong Guo
- 5 Department of Civil Affairs in Guizhou Province, Guizhou Province People`s Government, Guiyang, Guizhou, China
- Xin Tang
- 2 School of Second Clinical Medicine/The Second Affiliated Hospital, Yunnan University of Chinese Medicine, Kunming, Yunnan, China
- Zhijian Yang
- Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, PR China
- Jianwen Liu
- Rheumatology, Fujian Medical University Provincial Clinical Medical College, Fuzhou, Fujian, China
- Xiaoqin Zhang
- Northwest Women & Children Hospital Department of Obstetrics, Shaanxi, China
- Yuehua Huang
- Department of Infectious Diseases, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
- Guizhou Tao
- Shenghu He
- Moshui Chen
- Zhiming Yang
- Haiping Guo
- The University of Texas MD Anderson Cancer Center, Houston, TX, United States
- Xuming Yang
- Chuntong Wang
- Xiaoyong Qi
- School of Graduate, Hebei Medical University, Shijiazhuang, Hebei, China
- Hong Luan
- People`s Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, People`s Republic of China
- Qiang Xie
- Department of Nuclear Medicine, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China
- Dongmei Zhu
- Department of Hospital Infection Control, Chongqing Health Center for Women and Children, Chongqing 401147, China
- Yuanzhe Jin
- professor
- Likun Ma
- The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology, Hefei, China
- Xiaoling Su
- Department of Cardiology, Qinghai Provincial People’s Hospital, Xining, China
- Yongle Li
- Department of Cardiology, Tianjin Medical University General Hospital, Tianjin, China
- Deyong Long
- 2 Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University; National Clinical Research Center for Cardiovascular Diseases, Beijing, People`s Republic of China
- Baisong Yang
- Gengsheng Sang
- Bing Fu
- Buqiang Zhang
- Caidong Luo
- Changrong Liu
- Chuanliang Liang
- Chuanyan Zhang
- Chuanyang Wu
- Chunlin Lai
- Congliang Zhang
- Cui Bin
- Dawen Xu
- Fangfang Huang
- Fudong Gan
- Gengxin Li
- Guixia Zhang
- Guoqin Xin
- Guotuo Chen
- Guoxiong Chen
- Hailong Lin
- Haiyun Lin
- Honghua Deng
- Hongju Wang
- Hualing Liu
- Huifeng Wang
- Huimin Chu
- Jianghong Tao
- Jiaomei Yang
- Jifu Li
- Jinglan Diao
- Jingshan Zhao
- Jinru Wei
- Jinxing Yi
- Jinzi Su
- Jiong Tang
- Dangqing Yu
- Jiyan Yin
- Junping Deng
- Kalan Luo
- Lang Li
- Li Wei Li Jiang
- Lijun Meng
- Junqiang Cao
- Meisheng Lai
- Miao Tian
- Mingcheng Bo
- Minghua Han
- Naiyi Liang
- Qiaoqing Zhong
- Dajun Hu
- Qicun Wang
- Qinfeng Su
- Qing Hu
- Rong Chang
- Shaowu Ye
- Zhaohua Lu
- Shengxing Tang
- Shengyong Chen
- Shixin Ma
- Shuangbin Li
- Shuanli Xin
- Shudong Xia
- Shuhua Zhang
- Shuqiu Qu
- Shuren Ma
- Siding Wang
- Songbai Li
- Suxin Luo
- Suyan Zhou
- Tian Tuo
- Tianmin Du
- Wei Tuo
- Weiqing Fan
- Wenjun Yuan
- Xian’an Zhang
- Xiaolan Li
- Xiaolei Li
- Xiaoping Xu
- Xiaowei Peng
- Xiaoyun Feng
- Ximing Chen
- Xiufeng Chen
- Xudong Li
- Xuemei Peng
- Yanbo Niu
- Yanlie Zheng
- Yanzong Yang
- Liangqing Ge
- Jianqiang Peng
- Yingbi Su
- Yingchao Luo
- Yinglu Hao
- Yonglin Zhang
- Yuhuan Shi
- Yuqing Hou
- Zeqi Zheng
- Zesheng Xu
- Zewei Ouyang
- Zeyuan He
- Zhan Lv
- Zhanquang Li
- Zheng Ji
- Zhenguo Ji
- Zhihong Ou
- Zhongshan Wang
- DOI
- https://doi.org/10.1136/bmjopen-2024-088539
- Journal volume & issue
-
Vol. 15,
no. 2
Abstract
Objective To examine recent patterns regarding oral anticoagulant (OAC) use among patients hospitalised with atrial fibrillation (AF) and quantify the impact of insurance coverage for non-vitamin K oral anticoagulants (NOACs) on quality of care and care inequality regarding OAC use among hospitalised patients with AF.Design Interrupted time series analysis.Setting Hospitals in China.Participants A total of 36 393 patients hospitalised with non-valvular AF were involved between 2015 and 2019 across China.Primary and secondary outcome measures Outcome was the impact of insurance coverage for NOACs on quality of care regarding OAC prescription using interrupted time series analysis with segmented regression models.Results OAC prescription rate during hospitalisation was 52.1% (31.3% for warfarin and 20.8% for NOACs) in patients with high-risk AF and 66.3% (29.8% for warfarin and 36.5% for NOACs) in low-risk patients. Insurance coverage for NOACs was associated with an immediate 10.9% (95% CI 7.6% to 14.3%) increase in NOAC prescription and a 0.33% (95% CI 0.08% to 0.58%) increase in the slope of the secular trend of NOAC prescription among all the patients. Disparities in NOAC prescription among hospitals decreased from 18.9 before the insurance coverage for NOACs to 3.4 after that. Similar results were found in patients with high risk of stroke.Conclusion A large gap exists between clinical practice and guideline recommendations regarding OAC prescription among patients hospitalised with AF in China. Insurance coverage may be an effective healthcare strategy to improve quality of care and reduce care disparities regarding OAC prescription among patients with AF.Trial registration number NCT02309398.
