Resolution of hypogammaglobulinemia-associated recurrent Campylobacter bacteraemia after hematopoietic cell transplantation (HCT)

Abstract

Primary or secondary hypogammaglobulinemia is associated with persistent norovirus and Campylobacter infections despite immunoglobulin replacement therapy. Allogeneic hematopoietic cell transplantation for hematologic indications can lead to immune reconstitution by correcting a previously undiagnosed concurrent primary immunodeficiency.

Keywords

• Hypogammaglobulinemia
• Campylobacter
• norovirus
• hematopoietic cell transplant
• rituximab