CLINICAL PRESENTATION, DIAGNOSIS, AND TREATMENT IN PATIENTS WITH HIV INFECTION IN THE REPUBLIC OF ARMENIA

Abstract

Among 298 examinees with TB/HIV, there were most (86.2%) male patients aged 25-44 years. Social migrants were 65.7%. The infiltrative (25.8%) and disseminated (23.8%) forms of tuberculosis were common in its clinical structure. Extrapulmomary tuberculosis was diagnosed in 15.4% of cases. There were generalized lesions in 20.1%, including tuberculous meningitis (12.5%). 48.1% of the patients were found to be drug-unresponsive, mainly to isoniazid and rifampicin (59.6%). When CD4 counts were below 200 cells per µl of blood, extensive lung injuries were seen in 69.9%. Death occurred more frequently in disseminated (37.7%) and infiltrative (18.8%) pulmonary tuberculosis: its generalized process was a cause of death in one third of the patients.

Keywords

• туберкулез
• вич-инфекция
• лекарственная устойчивость