Role of Phosphodiesterases in Biology and Pathology 2.0

Mauro Giorgi; Manuela Pellegrini; Mara Massimi

doi:10.3390/ijms25105339

International Journal of Molecular Sciences (May 2024)

Role of Phosphodiesterases in Biology and Pathology 2.0

Mauro Giorgi,
Manuela Pellegrini,
Mara Massimi

Affiliations

Mauro Giorgi: Department of Biology and Biotechnology “C. Darwin”, Sapienza University of Rome, Piazzale A. Moro 5, 00185 Rome, Italy
Manuela Pellegrini: Institute of Biochemistry and Cell Biology, IBBC-CNR, Via E. Ramarini 32, 00015 Monterotondo (RM), Italy
Mara Massimi: Department of Life, Health and Environmental Sciences, University of L’Aquila, Via Vetoio, 67100 L’Aquila, Italy

DOI: https://doi.org/10.3390/ijms25105339
Journal volume & issue: Vol. 25, no. 10
p. 5339

Abstract

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Phosphodiesterases (PDEs) are ubiquitous enzymes that hydrolyse cAMP and cGMP second messengers temporally, spatially, and integratedly according to their expression and compartmentalization inside the cell [...]

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Published in International Journal of Molecular Sciences

ISSN: 1661-6596 (Print); 1422-0067 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General); Science: Chemistry
Website: http://www.mdpi.com/journal/ijms

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Abstract

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