Classification and Outcome Measures for Psoriatic Arthritis

Ying Ying Leung; Alexis Ogdie; Ana-Maria Orbai; William Tillett; Laura C. Coates; Vibeke Strand; Philip Mease; Dafna D. Gladman

doi:10.3389/fmed.2018.00246

Frontiers in Medicine (Sep 2018)

Classification and Outcome Measures for Psoriatic Arthritis

Ying Ying Leung,
Alexis Ogdie,
Ana-Maria Orbai,
William Tillett,
Laura C. Coates,
Vibeke Strand,
Philip Mease,
Dafna D. Gladman

Affiliations

Ying Ying Leung: Department of Rheumatology and Immunology, Singapore General Hospital, Duke-NUS Medical School, Singapore, Singapore
Alexis Ogdie: Division of Rheumatology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, United States
Ana-Maria Orbai: Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, United States
William Tillett: Royal National Hospital for Rheumatic Diseases and Department of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
Laura C. Coates: Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom
Vibeke Strand: Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, United States
Philip Mease: Department of Rheumatology Research, Swedish Medical Center, University of Washington, Seattle, WA, United States
Dafna D. Gladman: Division of Rheumatology and Krembil Research Institute, University Health Network, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada

DOI: https://doi.org/10.3389/fmed.2018.00246
Journal volume & issue: Vol. 5

Abstract

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Psoriatic arthritis (PsA) is an inflammatory arthritis with multiple manifestations: peripheral/axial arthritis, enthesitis, dactylitis, psoriasis, and nail involvement. From having an agreed upon classification criteria in 2006, the assessment of PsA has advanced from uncertainties to development and validation of numerous specific outcome measures. The Group for Research and Assessment of Psoriasis and Psoriatic arthritis (GRAPPA) has spearheaded the development of a core domain set and is now working on a core outcome measurement set to standardize outcome measures for PsA, that will provide guidance for use of instruments in randomized controlled trials (RCTs) and longitudinal observational studies (LOS). This article summarizes and updates these work processes to improve assessment of this multisystem complex rheumatologic disease.

Published in Frontiers in Medicine

ISSN: 2296-858X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: http://www.frontiersin.org/journals/medicine

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