Synthesis and Structural Study of a New β-Turn Inducer Peptidomimetic Incorporating 1-Amino-1-Aminomethylcyclohexane

Abstract

A new β-turn inducer peptidomimetic incorporating 1-amino-1-aminomethylcyclohexane (compound 3) was synthetized and structurally studied. It was established that there is a rapid conformational equilibrium between the expected β-turn inducer structure and other extended conformations.

Keywords

• amino acids
• peptides
• 1,2-diamines
• supramolecular chemistry