An in vitro model of neuronal ensembles

M. Angeles Rabadan; Estanislao Daniel De La Cruz; Sneha B. Rao; Yannan Chen; Cheng Gong; Gregg Crabtree; Bin Xu; Sander Markx; Joseph A. Gogos; Rafael Yuste; Raju Tomer

doi:10.1038/s41467-022-31073-1

Nature Communications (Jun 2022)

An in vitro model of neuronal ensembles

M. Angeles Rabadan,
Estanislao Daniel De La Cruz,
Sneha B. Rao,
Yannan Chen,
Cheng Gong,
Gregg Crabtree,
Bin Xu,
Sander Markx,
Joseph A. Gogos,
Rafael Yuste,
Raju Tomer

Affiliations

M. Angeles Rabadan: Department of Biological Sciences, Columbia University
Estanislao Daniel De La Cruz: Department of Biological Sciences, Columbia University
Sneha B. Rao: Mortimer B. Zuckerman Mind Brain and Behavior Institute, Columbia University
Yannan Chen: Department of Biological Sciences, Columbia University
Cheng Gong: Department of Biological Sciences, Columbia University
Gregg Crabtree: Mortimer B. Zuckerman Mind Brain and Behavior Institute, Columbia University
Bin Xu: Department of Psychiatry, Vagelos College of Physicians & Surgeons, Columbia University
Sander Markx: Department of Psychiatry, Vagelos College of Physicians & Surgeons, Columbia University
Joseph A. Gogos: Mortimer B. Zuckerman Mind Brain and Behavior Institute, Columbia University
Rafael Yuste: Department of Biological Sciences, Columbia University
Raju Tomer: Department of Biological Sciences, Columbia University

DOI: https://doi.org/10.1038/s41467-022-31073-1
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 17

Abstract

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Advances in 3D neuronal cultures have allowed unprecedented access to the mechanisms underlying brain diseases. This work describes the novel Modular Neuronal Network (MoNNet) system, which enables more complex studies of cortical neuronal ensemble dynamics.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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