Archives of Plastic Surgery (Jul 2022)

Adams-Oliver Syndrome: Vestigial Tail and Genetics Update

  • Victor Z. Zhu,
  • Emily Hansen-Kiss,
  • Jacqueline T. Hecht,
  • Phileemon E. Payne

DOI
https://doi.org/10.1055/s-0042-1751107
Journal volume & issue
Vol. 49, no. 04
pp. 517 – 522

Abstract

Read online

Adams-Oliver syndrome is a well-recognized autosomal dominant disorder for which mutations in six genes are etiologic, but account for only one-third of the cases. We report a patient with two genetic disorders; Adams-Oliver and Xp22.33 deletion syndromes, as well as a vestigial pseudotail. The presence of a pseudotail has not previously been reported in either of these genetic conditions. Absence of a molecular etiology underlying Adams-Oliver syndrome confirms that there are additional genetic causes to be identified.

Keywords