ENZYMES OF ENERGY METABOLISM IN BRAIN AND CHRONIC STRESS

Abstract

The development of changes in the activity of creatinkinase, aldolase and succinatdehydrogenase in brain cells under 30-day long stress induced by isolation and violated diurnal cycle has been studied. It was shown that these enzymes heterogeneously responded to 30-day long stress. Particular sensitivity was recorded in the case of succinatedehydrogenase, which showed the decline of activityin various sections of the brain by 60-80% on average. Unlike succinatedehydrogenase, aldolase activity increased on the 10th day of stress and then declined. Similar results were observed in relationto phosphokinase activity.

Keywords

• stress
• aldolase
• creatinkinase
• succinatdehidrogenase