Frontiers in Surgery (Jan 2023)

The role of endoscopic ultrasound-guided fine-needle aspiration/biopsy in the diagnosis of mediastinal lesions

  • Jingjing Zhou,
  • Jingjing Zhou,
  • Ting Cai,
  • Ting Cai,
  • Dongwen Wu,
  • Dongwen Wu,
  • Xiong Chen,
  • Xiong Chen,
  • Fen Wang,
  • Fen Wang

DOI
https://doi.org/10.3389/fsurg.2022.1065070
Journal volume & issue
Vol. 9

Abstract

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ObjectiveEndoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/FNB) is an accurate technique for sampling the pancreas and mediastinum. The aim of this study was to determine the value of EUS-FNA/FNB in the diagnosis of mediastinal lesions.MethodsData from 107 patients who underwent EUS-FNA/FNB for mediastinal lesions were evaluated.ResultsThe sensitivity, specificity, positive predictive value, and negative predictive value of EUS-FNA/FNB for mediastinal lesions were 92.00%, 100%, 100%, and 85%, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value of EUS-FNA for malignant mediastinal lesions were 92.00%, 100%, 100%, and 86.00%, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value of EUS-FNB for malignant mediastinal lesions were 92.00%, 100%, 100%, and 82.00%, respectively. Except for the discomfort caused by conventional gastroscopy, none of the patients had any complications, such as damage to surrounding large blood vessels or nerves.ConclusionEUS-FNA/FNB is an effective tool for diagnosing unknown mediastinal lesions, without any obvious complications.

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