Genetics and Molecular Biology (Jan 2007)

Atypical chromosome abnormalities in acute myeloid leukemia type M4

  • Agnes C. Fett-Conte,
  • Roseli Viscardi Estrela,
  • Cristina B. Vendrame-Goloni,
  • Andréa B. Carvalho-Salles,
  • Octávio Ricci-Júnior,
  • Marileila Varella-Garcia

DOI
https://doi.org/10.1590/S1415-47572007000100002
Journal volume & issue
Vol. 30, no. 1
pp. 6 – 9

Abstract

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This study reports an adult AML-M4 patient with atypical chromosomal aberrations present in all dividing bone marrow cell at diagnosis: t(1;8)(p32.1;q24.2), der(9)t(9;10)(q22;?), and ins(19;9)(p13.3;q22q34) that may have originated transcripts with leukemogenic potential.

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