Effects of SGLT2 inhibition via empagliflozin on cognitive and physical impairment in frail diabetic elders with chronic kidney disease

• Pasquale Mone,
• Germano Guerra,
• Angela Lombardi,
• Maddalena Illario,
• Antonella Pansini,
• Anna Marro,
• Salvatore Frullone,
• Alessandro Taurino,
• Daniela Sorriento,
• Veronica Verri,
• Guido Iaccarino,
• Gaetano Santulli

Affiliations

Pasquale Mone

Department of Medicine, Einstein-Mount Sinai Diabetes Research Center (ES-DRC), Fleischer Institute for Diabetes and Metabolism (FIDAM), Einstein Institute for Aging Research, Albert Einstein College of Medicine, New York City, New York, USA; ASL Avellino, Italy; University of Molise, Campobasso, Italy

Germano Guerra

University of Molise, Campobasso, Italy; International Translational Research and Medical Education (ITME) Consortium, Academic Research Unit, Naples, Italy

Angela Lombardi

Department of Medicine, Einstein-Mount Sinai Diabetes Research Center (ES-DRC), Fleischer Institute for Diabetes and Metabolism (FIDAM), Einstein Institute for Aging Research, Albert Einstein College of Medicine, New York City, New York, USA

Maddalena Illario

“Federico II” University, Naples, Italy

Antonella Pansini

ASL Avellino, Italy

Anna Marro

ASL Avellino, Italy

Salvatore Frullone

ASL Avellino, Italy

Alessandro Taurino

University of Bari, Italy

Daniela Sorriento

Department of Advanced Biomedical Sciences, “Federico II” University, Naples, Italy

Veronica Verri

University of Bari, Italy

Guido Iaccarino

“Federico II”University, Naples, Italy

Gaetano Santulli

Corresponding author at: Department of Advanced Biomedical Sciences, “Federico II” University, Naples, Italy.; Department of Advanced Biomedical Sciences, “Federico II” University, Naples, Italy; International Translational Research and Medical Education (ITME) Consortium, Academic Research Unit, Naples, Italy; Department of Medicine, Einstein-Mount Sinai Diabetes Research Center (ES-DRC), Fleischer Institute for Diabetes and Metabolism (FIDAM), Einstein Institute for Aging Research, Albert Einstein College of Medicine, New York City, New York, USA; Department of Molecular Pharmacology, Wilf Family Cardiovascular Research Institute, Einstein Institute for Neuroimmunology and Inflammation (INI), Albert Einstein College of Medicine, New York City, New York 10461, USA