Nature Communications (Jan 2023)

Generalized extinction of fear memory depends on co-allocation of synaptic plasticity in dendrites

  • Zhiwei Xu,
  • Erez Geron,
  • Luis M. Pérez-Cuesta,
  • Yang Bai,
  • Wen-Biao Gan

DOI
https://doi.org/10.1038/s41467-023-35805-9
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 17

Abstract

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How memories are modified by new experiences remain elusive. Here, authors show that specific or generalized modification of memories depends on whether synaptic changes associated with previous memories are segregated or co-exist in dendritic branches.