Communications Biology (Mar 2021)

Elucidation of transient protein-protein interactions within carrier protein-dependent biosynthesis

  • Thomas G. Bartholow,
  • Terra Sztain,
  • Ashay Patel,
  • D. John Lee,
  • Megan A. Young,
  • Ruben Abagyan,
  • Michael D. Burkart

DOI
https://doi.org/10.1038/s42003-021-01838-3
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 10

Abstract

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Using structural and computational analysis, Bartholow et al. perform a comprehensive residue-by-residue comparison of the protein-protein interactions in de novo fatty acid biosynthesis that occurs in E. coli. This study provides insights into molecular events that occur in carrier protein-dependent pathways.