International Journal of General Medicine (Nov 2021)

Validation of Coronary Artery Disease Reporting and Data System (CAD-RADS) and Application of Coronary Artery Calcium Data and Reporting System (CAC-DRS) as New Standardized Tools in the Management of Coronary Artery Disease Patients

  • Ebaid NY,
  • Khalifa DN,
  • Ragheb AS,
  • Abdelsamie MM,
  • Alsowey AM

Journal volume & issue
Vol. Volume 14
pp. 7503 – 7514

Abstract

Read online

Noha Yahia Ebaid,1 Dalia Nabil Khalifa,1 Ahmad Sabry Ragheb,1 Magdy Mohamad Abdelsamie,2 Ahmed Mohamed Alsowey1 1Department of Radiology, Faculty of Medicine, Zagazig University, Zagazig, Egypt; 2Department of Cardiology, Faculty of Medicine, Zagazig University, Zagazig, EgyptCorrespondence: Noha Yahia EbaidDepartment of Radiology, Faculty of Medicine, Zagazig University, Zagazig, EgyptTel +201064422995Email [email protected] and Objectives: The coronary artery disease reporting and data system (CAD-RADS) is intended to standardize the reporting of CCTA and the subsequent management guidelines of CAD. The present study was conducted to investigate the validation of CAD-RADS and the application of coronary calcium grading in CAD management.Patients and Methods: The current study is a single-center prospective study that involved 177 participants with chest pain who were submitted to coronary CT angiography (CCTA). Two reviewers independently assessed CCTA results and gave each patient a CAD-RADS category. The reference standard for determining the clinical utility of CAD-RADS was invasive coronary angiography (ICA). The inter-reviewer agreement (IRA) was tested using the intra-class correlation (ICC).Results: The study enrolled 111 cases with non-significant CAD and 66 cases with significant CAD based on ICA findings. According to the reviewer, the CAD-RADS had a sensitivity, specificity, and accuracy of 90.9 to 100%, 89.2 to 94.6%, and 93.16 to 93.2%, respectively, for predicting severe CAD. The IRA for CAD-RADS categories was excellent (ICC = 0.960). The best cut-off value for predicting severe CAD was CAD-RADS > 3. Significant relation between Ca and severe CAD (p< 0.001) was detected.Conclusion: The current study provides a good understanding of CAD-RADS as a standard tool with high diagnostic accuracy.Keywords: coronary, cardiovascular disease, Agatston, computed tomography, stenosis

Keywords