6-Hydroxy-4-(pyridin-3-yl)-5-(2-thienylcarbonyl)-6-trifluoromethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one

Abstract

In the title compound, C15H12F3N3O3S, the pyrimidine ring adopts a half-chair conformation with the mean plane formed by the ring atoms excluding the C atom bonded to thiophene-2-carbonyl group lying nearly perpendicular to the pyridine and thiophene rings, making dihedral angles of 84.91 (4) and 87.40 (5)°, respectively. The dihedral angle between the pyridine and thiophene rings is 54.44 (5)°. The crystal structure is stabilized by intermolecular O—H...O and N—H...N hydrogen bonds and weak C—H...O interactions further consolidate the structure.