ОПРЕДЕЛЕНИЕ РАННЕГО РЕМОДЕЛИРОВАНИЯ (СТАРЕНИЯ) СОСУДОВ

Abstract

428 practically healthy individuals and 301 patients with arterial hypertension have been examined by using a volumetric sphygmograph VaSera-1000 (Japan). In young individuals elevated stiffness of elastic arteries is associated with elevation of predominantly systolic blood pressure (BP) and elevated stiffness of muscular arteries is associated with elevation of diastolic BP. CAVI stiffness index > 7,6, ankle-brachial PWV > 11,9 m/s and heart-brachial PWV > 6,4 m/s are the criteria of early vascular aging in young people. Early remodeling of elastic arteries was observed in 47,1% patients with isolated systolic hypertension, in 31% patients with systole-diastolic hypertension and in 12,3% healthy subjects. Early remodeling of predominantly muscular type of arteries was observed in 54,4% patients with systole-diastolic hypertension, in 15,5% patients with isolated systolic hypertension and in 14,5% practically healthy subjects.

Keywords

• vascular remodeling
• stiffness
• pulse wave velocity
• arterial hypertension